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Since sodium/glucose cotransporter-2 (SGLT-2) inhibitor treatment reduces CV events as well (with the effect mainly driven by a reduction in heart failure complications), the individual risk of ischemic or heart failure complications should guide the choice of treatment

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This interactive tool combines an individuals genetic results for these two variants with demographics and medical history to estimate both weight loss and nausea likelihood based on data from 23andMe research participants

Some of the agents have also been shown to reduce the risk of major adverse cardiovascular events such as cardiovascular death, non-fatal myocardial infarction, and non-fatal stroke