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Description
In that extension, participants assigned to the 12 mg-to-maximum-tolerated-dose path averaged 30.3% body-weight reduction
Participants with class III obesity (BMI 40 or higher) were more likely to be late responders, meaning they needed more time to achieve significant weight loss
Freezing damages semaglutide and renders it ineffective
Keeping glucagon in check supports better overall glucose balance
If you want a practical overview of those issues, our post on GLP-1 side effects in 2026 covers what patients and providers commonly see
Potential Side Effects and Safety Considerations GLP-1 medications can cause side effects, and they are not appropriate for everyone
