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However, there was no improvement in fibrosis [127], possibly due to the short trial duration, a small study population, disease heterogeneity and the intrinsic limitations of liver biopsy (e.g., sample variability and reading across pathologists) [128]

A Phase 1 Multiple Dose Study of Tirzepatide in Chinese Patients with Type 2 Diabetes

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PMID: 33236115

For women exploring peptide options, the peptides for weight loss in women guide discusses how female hormonal factors can influence dose response, making moderate doses particularly effective for some women

That's accurate as far as it goes