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Several studies suggest that similar to lipids, reductions in food intake via intestinal protein in rodents are due to CCK release and subsequent activation of VANs, as (1) intestinal protein infusion increases CCK in rodents and humans 188,189

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For instance, Zepbound vials through LillyDirect cost between $299 and $449 per month, while Wegovy via NovoCare Pharmacy is around $349 per month - significantly less than retail prices that can exceed $1,000

Sleep deprivation exacerbates microglial reactivity and A deposition in a TREM2-dependent manner in mice

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