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Bariatric Surgery as a Gold Standard : Bariatric surgery remains the most effective intervention for achieving substantial and sustained weight loss, particularly in patients with severe obesity

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Hypoglycemia, while less common with tirzepatide alone due to its glucose-dependent mechanism, may occur, particularly in patients taking concurrent medications that affect blood glucose

9.4 Patient-centered outcomes: quantifying shared decision-making as evidence Polycystic Ovary Syndrome face complex trade-offs between body weight, aesthetic distress, fertility goals, psychological burden, and long-term cardiometabolic risks