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According to a Health Canada approval announced by Novo Nordisk on March 2, 2026, the new indication is based on a pooled analysis of four large clinical trials: SUSTAIN 6, PIONEER 6, FLOW, and SOUL

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MBio 14 , e01868-e1923 (2023)

Effect of nightly lower body negative pressure on choroid engorgement in a model of spaceflight-associated neuro-ocular syndrome: a randomized crossover trial

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