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Its anti-inflammatory mechanisms operate entirely through GLP-1R activation

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Running distance, food intake and body weight were measured daily before dosing of experimental compounds

[DOI] [PubMed] [Google Scholar] 58.Cooper ME

Its effects are mediated by activation of GLP-1 receptors (GLP-1Rs) in the central nervous system, which help regulate hunger signals that prompt people to eat when hungry and stop when satisfied (Fig