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Lilly and other followers will need to generate their own evidence to support cardiovascular benefits of their own obesity treatments to compete on coverage and use

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On the flipside, there are challenges: for example, concerns about cost to healthcare systems and equity of access for patients with the greatest unmet needs, or the possible impact on Medtech currently used by patients suffering from obesity related conditions for example knee replacements for overweight patients with eroded joints or CPAP machines for sleep apnoea, a complication of obesity