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Potential Cost Savings Brand-name weight loss medications can be expensive, with some GLP-1 receptor agonists costing hundreds (or even thousands) of dollars per month

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GLP-1 therapy is ideal for adults with a BMI of 27 or higher, those struggling with appetite control or metabolic issues, and individuals with prediabetes or type 2 diabetes

The research on GLP-1 drugs consistently shows that people who combine medication with structured exercise and nutrition coaching maintain more of their weight loss and lose more fat relative to muscle

As of 2025, retatrutide is not approved for use in the United Kingdom and is not available through the NHS or private prescription

10.1016/S2213-8587(22)00035-3 55 Rego-IraetaA.Prez-MndezL