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Based on data from RCTs in T1D and those with patients with T2D, initiation of a GLP-1RA should be followed by a decrease of total insulin dose to reduce events of hypoglycemia (71)

Therefore, early phase clinical trials must carefully assess safety and tolerability

Meta-analysis of results reported from SURPASS-1 to -5 clinical trials regarding discontinuation of study medications (A

Keep all medicines out of the sight and reach of children

They should also be avoided in patients with inflammatory bowel diseases ulcerative colitis is a good example

Each batch is independently HPLC-tested for purity and identity, with certificates of analysis available on request