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In population-based and veteran samples, adults with chronic pain were significantly more likely to have cannabis use disorder (CUD) than their non-pain counterparts

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In IBD, GLP-1RAs help modulate intestinal inflammation and improve clinical outcomes

They may offer a meaningful reduction in cravings and relapse risk across various addictive disorders." Dr Sophie Dix, Head of Medical Product and Content at Levity "GLP-1s appear to modulate activity in the mesolimbic dopamine system, the same circuitry implicated in both substance addiction and compulsive overeating

Weight loss interventions based on GLP-1RAs or structured exercise programs both improve share metabolic health, yet their effects on skeletal muscle appear to diverge

Fatigue is listed as a common adverse reaction (occurring in 5% of patients) in the FDA prescribing information for both Wegovy (semaglutide 2.4 mg) and Zepbound (tirzepatide), and occurred more frequently than with placebo in clinical trials