dpp-4 inhibitors vs. glp-1 agonist Mechanism of action for GIP, analogues and DPP4 in Renoprotective Effects of DPP-4 Inhibitors

Studies have shown that GLP-1 receptor agonists provide better glycemic control and lower the risks of hypoglycemia compared to other anti-diabetes medications

Insulin breakthrough In the end the final breakthrough was made by a team at the University of Toronto (figure 6)

Insulins lead to marked HbA 1c reductions and have a lower risk of GI effects but can lead to weight gain and are generally associated with a higher risk of hypoglycaemia than GLP-1RAs, which would present significant occupational implications for this patient

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Glycemic control appears similar between the two peptides

Gerstein HC, Bosch J, Dagenais GR, Daz R, Jung H, Maggioni AP, et al