glp-1 news Eli Lilly to seek approval of new weight-loss drug this year As interest in GLP-1 medication

Curr Opin Pharmacol

When the GIP receptor is activated, pancreatic insulin secretion capacity is enhanced, while fat metabolism and insulin sensitivity also improve

Other common side effects include headache, fatigue, dizziness, and heartburn

doi: 10.1016/j.ejphar.2015.09.024

Transition to Metabolic Constraint Collectively, GLP-1RA therapy is characterized by persistent reductions in nutrient inflow, increased reliance on lipid-derived substrates, suppression of anabolic pathways through AMPK signaling, and context-dependent modulation of adipose tissue lipolysis

Although EHR-recorded weight loss was generally less than the self-reported values, several factors may explain this discrepancy