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At 2.5 mg, youre on the lowest dose, and the primary goal here is tolerability, not dramatic weight loss

In Alzheimers disease, 6-month treatment with GLP-1 analog prevents decline of brain glucose metabolism: randomized, placebo-controlled, double-blind clinical trial

It works through two receptors: GLP-1 suppresses appetite and slows digestion, and GIP supports insulin sensitivity and metabolic efficiency

But chronic disease requiring indefinite pharmacological control and modified chronic disease are not the same category

Eligibility screening ensures that only patients who are medically appropriate for GLP-1s move forward

Bottom line: follow the guidance for your specific molecule not GLP-1s as a blanket