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Therefore, GLP-1R agonists might improve cognitive and memory function by reducing A deposition and tau hyperphosphorylation in the brain

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8 treated with 100 nmol kg 1 MK-801 ( n = 8 mice), 100 nmol kg 1 GLP-1 ( n = 8 mice), 100 nmol kg 1 GLP-1MK-801 ( n = 8 mice) or vehicle (isotonic saline, n = 8 mice) for 5 days

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