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According to Lillys trial results, patients who got weekly injections of Zepbound lost an average 20.2% of their body weight, or 50.3 pounds, after 72 weeks, compared with an average of 13.7% body weight, or 33.1 pounds, for those who got Wegovy

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Insurers often require prior authorization and step therapy , meaning patients must provide detailed proof of medical necessity and show theyve tried and failed with cheaper alternatives before approval