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At the end of 68 weeks, individuals in the semaglutide group lost an average of 14.9% of their body weight, compared with 2.4% in the control group (see below)

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Studies in patients with diabetes showed it also led to weight loss, raising the question of whether it would benefit people living with obesity who had not yet developed type 2 diabetes

However, research has shown that tirzepatide may produce greater average weight reduction in some patients

Studies of brand-name semaglutide show that stopping treatment typically leads to weight regainwhich is why we focus on body composition from day one