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Impact of liraglutide on amylase, lipase, and acute pancreatitis in participants with overweight/obesity and normoglycemia, prediabetes or type 2 diabetes: secondary analyses of pooled data from the SCALE Clinical Development Program [published correction appears in Diabetes Care 2018

Hygum K, Starup-Linde J, Langdahl BL

Although this new agent (cagrilintide/semaglutide) has not been addressed from a kidney perspective in clinical studies, it is known that amylin binds to G proteincoupled receptors in kidney and has been reported to influence proximal tubular sodium transport and activate the RAAS (83, 84)

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The FDA label advises stopping at least two months, or eight weeks, before trying to conceive so the medication has time to fully clear from the body
