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Obesity (Silver Spring) 28(6):10501061

An experimental model of GLP-1R knockout mice (GLP-1R-/-) [37] demonstrated that (GLP-1R-/-) mice exhibited only modest decreases in gonadal weight, while females exhibited delayed puberty, but subsequent fertility and sex-steroid secretion were normal

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A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction and Obesity (SUMMIT) (SUMMIT)

Wegovy is FDA approved specifically for weight management in people with obesity or those who are overweight with a related condition like high blood pressure or sleep apnea