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Together, Marks argues, this work 'established beyond any doubt, the hormonal nature of glucagon even though no endocrinological disease had yet been identified as a result of its over or under secretion' (Marks 2018)

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Meta-analyses of GLP-1 receptor agonists show that approximately 25% of weight lost consists of lean mass, with 75% coming from fat mass

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Ji L., Gao L., Jiang H., et al., Safety and Efficacy of a GLP1 and Glucagon Receptor Dual Agonist Mazdutide (IBI362) 9 Mg and 10 Mg in Chinese Adults With Overweight or Obesity: A Randomised, PlaceboControlled, MultipleAscendingDose Phase 1b Trial, EClinicalMedicine 54 (2022): 101691, 10.1016/j.eclinm.2022.101691

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[DOI] [PubMed] [Google Scholar] 105.Gerstein H.C., Sattar N., Rosenstock J., Ramasundarahettige C., Pratley R., Lopes R.D., Lam C.S.P., Khurmi N.S., Heenan L., Del P.S., et al

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