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But as key patents begin approaching expiry over the coming years, a new phase is unfolding the generics and biosimilar race

The primary outcomes were the percentage change and absolute change in body weight

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Conclusion Significant weight regain occurred 8 weeks after discontinuation of AOMs and was sustained through 20 weeks

Semaglutide was generally consistent with its known safety profile and showed some biomarker changes, but these did not translate into clinical benefit.