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Most patients need 12 to 18 months of active treatment plus an indefinite maintenance period

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Further, our findings may not be generalisable to youth with severe hyperglycaemia or those on chronic treatment and, due to limitations in sample size, we were only able to explore potential mediators of metformin response

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[W]hen men lose significant weight, particularly in the lower abdomen or pubic area, it can uncover more of the base of the penis that was previously buried in fat, she explained