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She was receiving tirzepatide 2.5 mg weekly, then titrated to 5 mg after one month, and this dose was maintained for over a year

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For researchers designing insulin resistance or beta-cell function models, tirzepatides dual-receptor mechanism offers a distinct pharmacological profile that semaglutide cannot replicate

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The theoretical benefits of delaying onset of kidney failure, in terms of years gained, for patients in FLOW treated with semaglutide vs placebo, if the amelioration of eGFR decline occurs a constant rate with semaglutide, is shown in Figure 4

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