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While those with obesity stand to reap considerable health benefits from fat loss, the potential benefits of fat loss among healthy-weight individuals are minimal and are unlikely to offset the sizable health risks associated with reduced lean mass

Smokers with genetic predispositions to nicotine addiction and lower dopamine sensitivity often struggle with both continued smoking and medication side effects

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T., & Drazner, M

Deficiencies in vitamin B12 (particularly in patients also taking metformin), iron, and other nutrients have been linked to cognitive symptoms