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But the additional GIP receptor binding domain makes tirzepatide a fundamentally different pharmacological tool

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It is important to note that the prescribing information for each GLP-1 RA medication includes warnings about potential delays in gastric emptying, along with side effects such as delayed gastric emptying, nausea, and vomiting

GLP-1(936) also exerted a glucagonostatic effect at 6 mmol/l glucose but not at 20 mmol/l glucose

de Candia, P

Reinforces the principle: change (rotate) your injection site with each injection