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Taking semaglutide did not increase risk of depressive symptoms or suicidal behavior in persons without known major mental health disorders in a new study.

Safety: GI AEs: 74% vs 42% AE discontinuation: ~7% vs ~6% Clinical takeaway: High-efficacy weight loss with a once-daily oral GLP-1RA potentially expanding uptake for patients who prefer to avoid injections

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GLP-1 medications are designed for long-term weight management, not short-term fixes

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