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Al-Samkari, H., & Kuter, D

Endocrinology 156: 255267, 2015

1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model

Novo measured Semagutide levels in the CSF and found that only about 0.1% of the drug enters the brain

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