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Dosage adjustments are recommended to lower the risk of hypoglycemia when switching patients to SEMGLEE from other insulin therapies [see Warnings and Precautions (5.3)].When switching from: Injection: 100 units/mL (U-100) clear and colorless solution available as: SEMGLEE is contraindicated: SEMGLEE prefilled pens must never be shared between patients, even if the needle is changed