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Interestingly, PC1 is also expressed in -cells and directs the intraislet GLP-1 production (1013)

Despite these promising findings, most gastroenterologists acknowledge that GLP-1 medications are not yet standard-of-care treatments for IBS, and patients should discuss potential benefits and risks with their healthcare providers before starting therapy

G., Atisso C., Sealls W., et al
metformin 1000 mg BID led to conflicting results on hyperandrogenism

The diversity and commonalities of gastroenteropancreatic neuroendocrine tumors
