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Most participants kept the weight off

But the company is monitoring how many patients increase to higher doses of the drug, particularly the 9-mg and 25-mg versions

Emerging evidence suggests the potential benefits of GLP-1 RAs in the treatment of IBD through enhanced mucosal healing and reduced inflammation

Compared with DPP-4 inhibitor users, those taking GLP-1RAs had a 13% lower risk of rheumatoid arthritis, 18% lower risk of gout and a modest reduction in osteoarthritis incidence over one year

Attempt the dose increase again after the hold or reduction period

We uncover topics around weight loss, side effects of different GLP-1 RAs, and concerns about drug access and supply, with a mainly neutral-to-positive view of GLP-1 RAs, highlighting the role of an AI-enabled pipeline to help monitor for emerging side effects, uncover public sentiment, and guide future directions for research and public health efforts