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278 Importantly, GLP-1 RAs also exhibit neuroprotective potential

UK Prospective Diabetes Study (UKPDS) Group: Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

Waddell N, Pajic M, Patch AM, Chang DK, Kassahn KS, Bailey P, Johns AL, Miller D, Nones K, Quek K, Quinn MC, Robertson AJ, Fadlullah MZ, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, Manning S, Nourse C, Grimmond SM

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If you experience severe nausea, vomiting, persistent diarrhea, or allergic symptoms (rash, swelling, difficulty breathing) while taking both medications, seek immediate medical attention

While the few clinical trials completed so far have shown mixed results, the overall signals are encouraging