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Metformin remains the first-line oral agent for most patients with type 2 diabetes, unless contraindicated, and should be continued alongside any alternative therapy unless there are specific reasons for discontinuation, as recommended by NICE

Tatum and colleagues including senior author Bernard F

More specifically, beinaglutide restored the richness and diversity of the gut flora in patients with obesity, decreasing the relative abundance of Prevotella , Lachnospira , and Dialister while increasing that of Blautia A and Gemmiger A

Crucially, the research identifies food noise as one of the key reasons that weight loss attempts so frequently stall or fail

The other 40% either cycle between periods on and off medication, or attempt lifestyle maintenance alone
