glp-1 agonist alcohol receptor agonists show promise in treating substance use disorders GLP-1 agonists help reduce alcohol

(PubMed) Side Effect Profile GI effects (nausea, vomiting, diarrhea/constipation) Similar GI-class effects are commonly reported (especially during dose escalation phases in medical use contexts)

And nobody has yet figured out what happens when genuinely effective obesity drugs become genuinely affordable at scale

128 Our previous data showed that central IR may significantly affect the expression of synaptic plasticity proteins, such as postsynaptic density protein-95 (PSD95), Arc, synapsin1, BDNF, resulting in the impaired synaptic plasticity of neurons and decreased learning and memory ability (data not shown)

[DOI] [PubMed] [Google Scholar] 2.Creutzfeldt W., The incretin concept today

All data shown as the mean SEM

Another study showed the extract to be an effective mimetic of insulin, that works synergistically with insulin (receptor agonsist)