restarting glp 1 Could stopping and GLP-1 drugs have side effects? Truveta leads first study to

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Our 2030 estimates contemplate global penetration into the addressable type 2 diabetes and obesity markets of only 8% and 2%, respectively (from about 3% and 0.2% in 2023). Uptake would likely be greater if these drugs could be consumed in oral form rather than injected, adds the report, An oral weight loss agent would likely be well-received in the primary care setting and could alleviate pressure on supply chains

GLP-1 medications like Wegovy (semaglutide) and Zepbound (tirzepatide) have changed the way people approach weight loss

Au HCT, Zheng YJ, Le GH, Wong S, Phan L, Teopiz KM, Kwan ATH, Rhee TG, Rosenblat JD, Ho R, McIntyre RS (2025) A systematic review in effects of glucagon-like peptide-1 (GLP-1) mono-agonists on functional connectivity: Target engagement and rationale for the development in mental disorders

36 While a calorie deficit is necessary for weight loss, a prolonged calorie deficit can have adverse effects on energy expenditure, 34 leading to decreased mood and energy level