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TTP, Sep 2023

Zuranolone (Zurzuvae, Biogen) has been approved by the MHRA to treat postnatal depression

Holst suspects this may help explain how GLP-1 agonists influence organs that lack direct receptor expression, including parts of the central nervous system

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Furthermore, these augmented non-responders ultimately attained comparable outcomes to patients who initially responded well to behavioral therapy alone

What clinical circumstances make GLP-1 receptor agonists better than metformin for managing Type 2 diabetes, and how do these circumstances influence patient outcomes