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It will also be interesting to see whether and how differences in headline figures for weight loss delivered by different therapies translate into CV benefits and, especially, if this would give more potent therapies than Wegovy a competitive advantage

Clinical Importance: Oral semaglutide is the first oral GLP-1 receptor agonist, combining meaningful HbA1c reduction, clinically relevant weight loss, and favorable blood-pressure effects in a once-daily tablet

Many of our diseases are made worse by obesity, notably rheumatoid arthritis, psoriatic arthritis, and osteoarthritis

Phase two trials of the US biotech companys obesity pill showed weight loss of 12.2 percent but a higher rate of patient drop-off compared to a placebo.

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