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There are supportive clinical trials in T2DM patients of GLP-1 agonist mediated reduction in plaque burden, size and composition [62]

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These findings suggest that structural or functional dysregulation of the hypothalamus plays a critical role in the hyperphagia and obesity associated with PWS

Because semaglutide influences pancreatic beta cells to release insulin in a glucose-dependent manner, questions naturally arise about its broader effects on pancreatic tissue

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