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Overall, these drugs are able to lower glucose (mainly postprandial) and glycosylated hemoglobin blood levels, simultaneously promoting weight loss

Pi-Sunyer et al

And some people have dropped out of studies because they feel theyre losing too much weight

Obesity contributes to up to half of new diabetes cases annually in the United States

Although best known for its insulinotropic and weight lowering action, GLP-1R agonism also confers a series of beneficial effects on the cardiovascular system in rodents

B 57 , 289300 (1995)
