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To minimise problems: Sip water regularly and aim for around 2 to 3 litres per day, unless your doctor advises otherwise Consider water rich foods such as soups, cucumbers and watermelon Start with smaller meals, eating slowly and stopping at the first sign of comfortable fullness Focus on softer, easy to digest foods if you feel unwell 4

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This confirms that weight loss with retatrutide does not plateau at the primary timepoint and continues to improve with extended treatment

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What stands out to me is that the conversation is increasingly moving beyond weight loss alone

Diabetologia 53 (1), 153159