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[DOI] [PubMed] [Google Scholar] 8.Force U.S.P.S.T., Grossman D.C., Bibbins-Domingo K., Curry S.J., Barry M.J., Davidson K.W., Doubeni C.A., Epling J.W., Jr., Kemper A.R., Krist A.H., et al
It reflects a straightforward clinical reality: these medications interact with several organ systems simultaneously, and some patients have underlying conditions that make prescribing them without baseline data genuinely unsafe

From the point of view of clinical relevance, pathophysiological responses to GLP-1 demonstrated in current study including acute increases in RSNA, MAP and HR and decreases in diuresis and natriuresis, all features that are likely to be unfavorable and might contribute to a greater risk for HF

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