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Despite the potential clinical benefits of GLP-1RA plus SGLT2i combination therapy in patients with T2DM, several factors may delay this combination to become a common practice soon, such as reimbursement and costs associated with polypharmacy
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Division of Cardiothoracic Surgery, Department of Surgery, The Warren Alpert Medical School of Brown University OPEN ACCESS PUBLISHED: 30 November 2025 CITATION: Zheng,

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