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Obesity is a complex chronic disease that requires multimodal and usually lifelong treatment, i.e

J Transl Med (2021) 19(1):515

Most GLP-1 medications start at a low dose and gradually increase every four weeks to minimize gastrointestinal side effects

GLP-1 RA treatment in Parkinsons Disease and Alzheimers Disease)
However, more recent evidence shows renoprotective evidence and slowing of chronic kidney disease progression as seen in a meta-analysis released in 2023 [70]
There is science and its applications, which are related to one another as the fruit is related to the tree that has borne it." It's very hard to predict the usefulness of knowledge that seems useless today