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IL-21R signaling has been shown to promote MASH-HCC via the induction of immunosuppressive IgA + B cells [23]

Crosby RD, Kolotkin RL, Williams GR
Dales 2 , UHL Diabetes and Pregnancy Team

Some patients report that reflux symptoms worsen when starting GLP-1 receptor agonists, though individual responses vary considerably

I include only the highest dose options because patients typically choose the highest potency medication because they provide the lowest price per unit of the medication

There were sufficient reports that the FDA issued a warning in 2023 that GLP-1 receptor agonists (including Ozempic) may increase the risk of alopecia
