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And there may be some people previously unresponsive to existing therapies who would benefit from trying orforglipron instead
The American Journal of PhysiologyEndocrinology and Metabolism

The addition of tirzepatide to insulin glargine was evaluated in the SURPASS-5 study, focusing on patients with T2DM who had inadequate glycemic control

Association between glucagon-like Peptide-1 receptor agonists exposure and intraocular pressure change: GLP-1 receptor agonists and intraocular pressure change
Accelerate refers to increasing dose intensity when clinical indicators suggest that stronger receptor activation may be appropriate
