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While a 2024 FDA Drug Safety Communication did not find an increased association between depressive symptoms and suicidal thoughts in patients taking GLP-1 RAs, it nonetheless recommended that patients be closely monitored for such symptoms until more data is available

Figure 4 Discussion Our study provides additional support that there is a higher percentage of patients on GLP-1RA with retained gastric contents on EGD

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No new or unexpected safety signals emerged beyond what we know from GLP-1 and dual-agonist therapies

Most plasma centers require medical review before clearing donors on semaglutide

The company is currently running a phase 2 master protocol study (NCT06143956) of mazdutide in a largely US-based population of overweight and obese adults, alongside other Eli Lilly obesity drugs