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Description
A phase 2B trial (NCT02279524) showed that although aramchol 600 mg had no impact on liver fat fraction, it provided favorable outcomes in liver fibrosis and ALT levels, suggesting it may be a promising therapy for MASH with fibrosis
Clinical trials including the STEP program demonstrated weight loss at all semaglutide doses above placebo, with greater loss at higher doses
N Engl J Med 392: 427437
Front Syst Neurosci
10.1016/S0140-6736(09)62124-3
It usually resolves without intervention
