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A year after stopping taking glucagon-like peptide 1 (GLP-1) receptor agonists like semaglutide (WeGovy) and tirzepatide (Mounjaro) people regain on average 60% of their lost weight, the latest analysis found

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity Proceedings of the National Academy of Sciences 2013;110(22):9066-9071 doi:10.1073/pnas.1219451110 (Animal study) Plovier H, Everard A, Druart C, et al

These medications have a low risk of causing low blood sugar when used alone but may increase this risk when combined with insulin or sulfonylureas

More than 30 million Americans have tried one of these GLP-1 agonist drugs

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As additional research becomes available, recommendations related to the use of glucose-lowering agents to optimize glycemic, cardiovascular, and renal outcomes will undoubtedly continue to evolve and inform patient-centered diabetes care