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Carbonic anhydrase may originate from retinal hemorrhages and erythrocyte lysis and may activate the kallikrein-mediated inflammatory cascade, contributing to the development of DME

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The brain was submerged in cold (4C) buffer (140 mM NaCl, 5 mM KCl, 2 mM CaCl 2 , 5 mM glucose, and 10 mM HEPES) and continually gassed with 100% O 2

We made further amendments on the basis of version 1 dated November 2019, and we will communicate the protocol amendments to the Clinical Trials