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Encouragingly, the number of disease-modifying trials increased over the decade and accounted for more than half of all new trial registrations between 2022 and 2024

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Firefighting crews work to contain flames threatening communities, while smoke travels south, clouding skies over New York and New Jersey, including near the venue for the 2026 World Cup final

The reality, however, is quite different

Compounding of semaglutide is also subject to FDA rules that have tightened since the semaglutide shortage was declared resolved in 2025, so availability is not guaranteed and depends on regulatory and supply conditions