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Historically, anti-obesity drugs have shown a lot of negative side effects and only moderate efficacy
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This work was supported by a National Priorities Research Program grant (NPRP 14 S-0311210033

In AD, A damages microglia, produces inflammatory cytokines and chemokines, and affects surrounding CNS resident cells (astrocytes, oligodendrocytes, and neurons), which may aggravate tau pathology and ultimately lead to neurodegeneration and neuron loss

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